Neoplastic inhibitors - メーカー・企業と業務用製品 | イプロスものづくり

Inhibitor of angiogenesis by CD9 expression suppression (siRNA) [Kagoshima University]

Gene therapy technology (CD9 siRNA) that realizes innovative angiogenesis inhibitors!

We would like to introduce a "angiogenesis inhibitor" through the suppression of CD9 expression (siRNA). As a result of verification using a rat corneal model, it was found that the suppression of CD9 expression significantly inhibited both the motility and invasiveness of endothelial cells. Additionally, the angiogenesis inhibitory effect was confirmed in both systems with different angiogenic factors (HGF and VEGF). 【Key Points】 ■ Confirmed significant suppression of motility and invasiveness in vitro ■ Clear angiogenesis inhibitory effect confirmed in vivo ■ An angiogenesis inhibitory therapeutic agent with universal effects against different angiogenic factors *For more details, please download the PDF or feel free to contact us.